Description
| 抗体名: | EAF2 Antibody, Biotin conjugated (PACO47005) |
| 抗体コード: | PACO47005 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human ELL-associated factor 2 protein (6-100AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. |
| シノニム: | ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein), EAF2, TRAITS |
| UniProt Protein Function: | EAF2: Acts as a transcriptional transactivator of TCEA1 elongation activity. Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. Belongs to the EAF family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q13.33 Cellular Component: transcription elongation factor complex; nuclear speck Molecular Function:protein binding Biological Process: transcription, DNA-dependent; apoptosis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of cell growth |
| UniProt Code: | Q96CJ1 |
| NCBI GenInfo Identifier: | 73919269 |
| NCBI Gene ID: | 55840 |
| NCBI Accession: | Q96CJ1.1 |
| UniProt Related Accession: | Q96CJ1 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | ELL-associated factor 2 |
| NCBI Synonym Full Names: | ELL associated factor 2 |
| NCBI Official Symbol: | EAF2 |
| NCBI Official Synonym Symbols: | U19; BM040; TRAITS |
| NCBI Protein Information: | ELL-associated factor 2 |
| UniProt Protein Name: | ELL-associated factor 2 |
| UniProt Synonym Protein Names: | Testosterone-regulated apoptosis inducer and tumor suppressor protein |
| Protein Family: | ELL-associated factor |
| UniProt Gene Name: | EAF2 |
| UniProt Entry Name: | EAF2_HUMAN |
