Description
| 抗体名: | E2F8 Antibody (PACO08976) |
| 抗体コード: | PACO08976 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human E2F8 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | E2F transcription factor 8;E2F8;FLJ23311 ; |
| UniProt Protein Function: | E2F8: Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Belongs to the E2F/DP family. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: transcription factor complex; nucleus Molecular Function:protein binding; protein homodimerization activity; transcription corepressor activity; transcription factor activity Biological Process: cell proliferation; transcription, DNA-dependent; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; sprouting angiogenesis; cell cycle comprising mitosis without cytokinesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cytokinesis; placenta development |
| NCBI Summary: | This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012] |
| UniProt Code: | A0AVK6 |
| NCBI GenInfo Identifier: | 121949436 |
| NCBI Gene ID: | 79733 |
| NCBI Accession: | A0AVK6.1 |
| UniProt Secondary Accession: | A0AVK6,Q2VPJ3, Q3C1U6, Q5BKY4, Q8N340, Q9H5M0, A8K9H3 |
| UniProt Related Accession: | A0AVK6 |
| Molecular Weight: | 867 |
| NCBI Full Name: | Transcription factor E2F8 |
| NCBI Synonym Full Names: | E2F transcription factor 8 |
| NCBI Official Symbol: | E2F8 |
| NCBI Official Synonym Symbols: | E2F-8 |
| NCBI Protein Information: | transcription factor E2F8; E2F family member 8 |
| UniProt Protein Name: | Transcription factor E2F8 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | E2F8 |
| UniProt Entry Name: | E2F8_HUMAN |
