| UniProt Protein Function: | May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. |
| NCBI Summary: | The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y4J8 |
| NCBI GenInfo Identifier: | 229462840 |
| NCBI Gene ID: | 1837 |
| NCBI Accession: | Q9Y4J8.2 |
| UniProt Secondary Accession: | Q9Y4J8,O15332, O15333, O75697, A8K541, A8MSZ0, A8MUY4 B4DGS6, B4DIR0, B4DIU8, M0QYX6, M0R397, |
| UniProt Related Accession: | Q9Y4J8 |
| Molecular Weight: | 58,472 Da |
| NCBI Full Name: | Dystrobrevin alpha |
| NCBI Synonym Full Names: | dystrobrevin alpha |
| NCBI Official Symbol: | DTNA |
| NCBI Official Synonym Symbols: | DTN; DRP3; DTN-A; LVNC1; D18S892E |
| NCBI Protein Information: | dystrobrevin alpha |
| UniProt Protein Name: | Dystrobrevin alpha |
| UniProt Synonym Protein Names: | Alpha-dystrobrevin; Dystrophin-related protein 3 |
| Protein Family: | Dystrobrevin |
| UniProt Gene Name: | DTNA |
| UniProt Entry Name: | DTNA_HUMAN |
