Description
| 抗体名: | DPY30 Antibody (PACO40374) |
| 抗体コード: | PACO40374 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Protein dpy-30 homolog protein (1-99AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO40374 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO40374 at dilution of 1:100. |
| バックグラウンド: | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid, induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. |
| シノニム: | Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L), DPY30 |
| UniProt Protein Function: | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. |
| NCBI Summary: | This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q9C005 |
| NCBI GenInfo Identifier: | 14211889 |
| NCBI Gene ID: | 84661 |
| NCBI Accession: | NP_115963.1 |
| UniProt Secondary Accession: | Q9C005,D6W578, |
| UniProt Related Accession: | Q9C005 |
| Molecular Weight: | 11,250 Da |
| NCBI Full Name: | protein dpy-30 homolog isoform 1 |
| NCBI Synonym Full Names: | dpy-30, histone methyltransferase complex regulatory subunit |
| NCBI Official Symbol: | DPY30 |
| NCBI Official Synonym Symbols: | Cps25; Saf19; HDPY-30 |
| NCBI Protein Information: | protein dpy-30 homolog |
| UniProt Protein Name: | Protein dpy-30 homolog |
| UniProt Synonym Protein Names: | Dpy-30-like protein; Dpy-30L |
| Protein Family: | DPY30 domain-containing protein |
| UniProt Gene Name: | DPY30 |
| Antibodies |
| Anti-DPY30 Antibody (CAB17796) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
