Description
| 抗体名: | DPH7 Antibody, HRP conjugated (PACO47043) |
| 抗体コード: | PACO47043 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Diphthine methyltransferase protein (210-325AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). |
| シノニム: | Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (WD repeat-containing protein 85), DPH7, C9orf112 WDR85 |
| UniProt Protein Function: | WDR85: Plays a role in the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 which can be ADP- ribosylated by diphtheria toxin and by Pseudomonas exotoxin A. Belongs to the WD repeat WDR85 family.Chromosomal Location of Human Ortholog: 9q34.3Biological Process: peptidyl-diphthamide biosynthetic process from peptidyl-histidine |
| UniProt Protein Details: | |
| NCBI Summary: | WDR85 is a WD repeat-containing protein that plays a role in the first step of diphthamide biosynthesis (Carette et al., 2009 [PubMed 19965467]).[supplied by OMIM, Feb 2010] |
| UniProt Code: | Q9BTV6 |
| NCBI GenInfo Identifier: | 68565266 |
| NCBI Gene ID: | 92715 |
| NCBI Accession: | Q9BTV6.2 |
| UniProt Secondary Accession: | Q9BTV6,Q96AB7 |
| UniProt Related Accession: | Q9BTV6 |
| Molecular Weight: | 50,575 Da |
| NCBI Full Name: | Diphthine methyltransferase |
| NCBI Synonym Full Names: | diphthamide biosynthesis 7 |
| NCBI Official Symbol: | DPH7 |
| NCBI Official Synonym Symbols: | RRT2; WDR85; C9orf112 |
| NCBI Protein Information: | diphthine methyltransferase |
| UniProt Protein Name: | Diphthine methyltransferase |
| UniProt Synonym Protein Names: | Diphthamide biosynthesis protein 7; WD repeat-containing protein 85 |
| Protein Family: | Diphthine methyltransferase |
| UniProt Gene Name: | DPH7 |
| UniProt Entry Name: | DPH7_HUMAN |