Description
| 抗体名: | DNAJB4 Antibody (PACO08880) |
| 抗体コード: | PACO08880 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human DNAJB4 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | DnaJ (Hsp40) homolog, subfamily B, member 4;DNAJB4;DNAJW;DjB4;HLJ1 ; |
| UniProt Protein Function: | DNAJB4: Probable chaperone. Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. By heat shock. Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 1p31.1 Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane Molecular Function:chaperone binding; protein binding; unfolded protein binding Biological Process: protein folding; response to heat; response to unfolded protein |
| NCBI Summary: | The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
| UniProt Code: | Q9UDY4 |
| NCBI GenInfo Identifier: | 8928155 |
| NCBI Gene ID: | 11080 |
| NCBI Accession: | Q9UDY4.1 |
| UniProt Secondary Accession: | Q9UDY4,Q13431, B2R824, |
| UniProt Related Accession: | Q9UDY4 |
| Molecular Weight: | 37,807 Da |
| NCBI Full Name: | DnaJ homolog subfamily B member 4 |
| NCBI Synonym Full Names: | DnaJ heat shock protein family (Hsp40) member B4 |
| NCBI Official Symbol: | DNAJB4 |
| NCBI Official Synonym Symbols: | DjB4; HLJ1; DNAJW |
| NCBI Protein Information: | dnaJ homolog subfamily B member 4 |
| UniProt Protein Name: | DnaJ homolog subfamily B member 4 |
| UniProt Synonym Protein Names: | Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein |
| Protein Family: | DnaJ homolog subfamily |
| UniProt Gene Name: | DNAJB4 |
| UniProt Entry Name: | DNJB4_HUMAN |
