Description
| 抗体名: | DNAJB2 Antibody (PACO45319) |
| 抗体コード: | PACO45319 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human DnaJ homolog subfamily B member 2 protein (215-324AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: DNAJB2 antibody at 1.18µg/ml. Lane 1: 293T whole cell lysate. Lane 2: PC-3 whole cell lysate. Lane 3: A431 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36, 31 kDa. Observed band size: 36 kDa.. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO45319 at dilution of 1:100. |
| バックグラウンド: | cytosol, inclusion body, nucleus, chaperone binding, Hsp70 protein binding, polyubiquitin binding, proteasome binding, ubiquitin protein ligase binding, unfolded protein binding, ER-associated ubiquitin-dependent protein catabolic process |
| シノニム: | DnaJ homolog subfamily B member 2 (Heat shock 40 kDa protein 3) (Heat shock protein J1) (HSJ-1), DNAJB2, HSJ1 HSPF3 |
| UniProt Protein Function: | DNAJB2: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 2q35 Cellular Component: proteasome complex; inclusion body; nucleus; cytosol Molecular Function:protein binding; chaperone binding; unfolded protein binding; Hsp70 protein binding; polyubiquitin binding Biological Process: negative regulation of cell proliferation; ER-associated protein catabolic process; protein folding; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein refolding; negative regulation of cell growth; response to unfolded protein Disease: Spinal Muscular Atrophy, Distal, Autosomal Recessive, 5; Charcot-marie-tooth Disease, Axonal, Type 2t |
| NCBI Summary: | This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011] |
| UniProt Code: | P25686 |
| NCBI GenInfo Identifier: | 158518384 |
| NCBI Gene ID: | 3300 |
| NCBI Accession: | P25686.3 |
| UniProt Related Accession: | P25686 |
| Molecular Weight: | Predicted Molecular Mass: 34.3kDaAccurate Molecular Mass: 37kDa |
| NCBI Full Name: | DnaJ homolog subfamily B member 2 |
| NCBI Synonym Full Names: | DnaJ heat shock protein family (Hsp40) member B2 |
| NCBI Official Symbol: | DNAJB2 |
| NCBI Official Synonym Symbols: | HSJ1; CMT2T; DSMA5; HSJ-1; HSPF3 |
| NCBI Protein Information: | dnaJ homolog subfamily B member 2 |
| UniProt Protein Name: | DnaJ homolog subfamily B member 2 |
| UniProt Synonym Protein Names: | DnaJ protein homolog 1; Heat shock 40 kDa protein 3; Heat shock protein J1; HSJ-1 |
| UniProt Gene Name: | DNAJB2 |
| UniProt Entry Name: | DNJB2_HUMAN |
| Antibodies | ELISA Kits |
| Anti-DNAJB2 Antibody (CAB10345) | Human HSP-40 (Heat Shock Protein 40) CLIA Kit (HUES01028) |
| DNAJB2 Antibody (PACO08878) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
