Description
| 抗体名: | DNAJB11 Antibody (PACO06473) |
| 抗体コード: | PACO06473 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from the Internal region of human ERdj3. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of NIH-3T3 K562 Jurkat cells using ERdj3 Polyclonal Antibody. |
 | Western Blot analysis of Hela cells using ERdj3 Polyclonal Antibody. |
| シノニム: | DNAJB11; EDJ; ERJ3; HDJ9; PSEC0121; DnaJ homolog subfamily B member 11; APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; ER-associated dnaJ protein 3; ERdj3; ERj3p; HEDJ; Human |
| UniProt Protein Function: | DNAJB11: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Endoplasmic reticulum; RNA processing; Chaperone Chromosomal Location of Human Ortholog: 3q27.3 Cellular Component: membrane; endoplasmic reticulum; endoplasmic reticulum lumen; nucleus Molecular Function:protein binding; unfolded protein binding Biological Process: unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; protein folding; unfolded protein response; mRNA modification |
| NCBI Summary: | This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q9UBS4 |
| NCBI GenInfo Identifier: | 18203497 |
| NCBI Gene ID: | 51726 |
| NCBI Accession: | Q9UBS4.1 |
| UniProt Secondary Accession: | Q9UBS4,Q542Y5, Q542Y9, Q6IAQ8, Q96JC6, |
| UniProt Related Accession: | Q9UBS4 |
| Molecular Weight: | 358 |
| NCBI Full Name: | DnaJ homolog subfamily B member 11 |
| NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily B, member 11 |
| NCBI Official Symbol: | DNAJB11 |
| NCBI Official Synonym Symbols: | DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080 |
| NCBI Protein Information: | dnaJ homolog subfamily B member 11; DnaJ protein 9; APOBEC1-binding protein 2; ER-resident protein ERdj3; PWP1-interacting protein 4; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; endoplasmic reticulum DNA J domain-containing protein 3 |
| UniProt Protein Name: | DnaJ homolog subfamily B member 11 |
| UniProt Synonym Protein Names: | APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4 |
| Protein Family: | DnaJ homolog subfamily |
| UniProt Gene Name: | DNAJB11 |
| UniProt Entry Name: | DJB11_HUMAN |
