Description
| Product Name: | Dengue Polyvalent Recombinant Protein |
| Product Code: | RPPB5683 |
| Size: | 0.5mg |
| Species: | Dengue |
| Target: | Polyvalent |
| Source: | Escherichia Coli |
| Formulation: | Phosphate buffered saline, pH-7.4 and 0.05% NaN3. |
| Stability: | Polyvalent Dengue although stable at 4°C for 1 week, should be stored below -18°C.�Please prevent freeze thaw cycles. |
| Purity: | Protein is >95% pure as determined by 12% PAGE (coomassie staining). |
Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
Polyvalent dengue antigen is a 22kDa protein that contains 4 dengue antigen subtypes, produced in E.coli and fused to a 6xHis Tag. The immunoreactive peptide span from the viral envelope to the non-functional region. The polyvalent dengue antigen consists of 25% recombinant antigen from each of the dengue subtypes in their composition. The Polyvalent dengue antigen detects all four dengue subtypes. The sensitivity and specificity could reach approximately 93% and 96% in dengue IgG and IgM ELISA assay.
