Description
| 抗体名: | DDX6 Antibody, Biotin conjugated (PACO47377) |
| 抗体コード: | PACO47377 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Probable ATP-dependent RNA helicase DDX6 protein (1-149AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts. |
| シノニム: | Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK), DDX6, HLR2 RCK |
| UniProt Protein Function: | DDX6: an oncogenic ATP-dependent helicase of the DEAD box family. Interacts with argonaute proteins, Ago1 and Ago2, and is a general repressor of translation in human cells by miRNA-induced gene silencing. In the process of mRNA degradation, may play a role in mRNA decapping. |
| UniProt Protein Details: | Protein type:RNA processing; Oncoprotein; EC 3.6.4.13; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: intracellular membrane-bound organelle; membrane; stress granule; cytoplasm; cytosol Molecular Function:protein domain specific binding; protein binding; helicase activity; ATP binding; RNA helicase activity Biological Process: gene expression; cytoplasmic mRNA processing body assembly; mRNA catabolic process, deadenylation-dependent decay |
| NCBI Summary: | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
| UniProt Code: | P26196 |
| NCBI GenInfo Identifier: | 116241327 |
| NCBI Gene ID: | 1656 |
| NCBI Accession: | P26196.2 |
| UniProt Secondary Accession: | P26196,P54823, |
| UniProt Related Accession: | P26196 |
| Molecular Weight: | 483 |
| NCBI Full Name: | Probable ATP-dependent RNA helicase DDX6 |
| NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| NCBI Official Symbol: | DDX6 |
| NCBI Official Synonym Symbols: | P54; RCK; HLR2 |
| NCBI Protein Information: | probable ATP-dependent RNA helicase DDX6; DEAD box-6; oncogene RCK; DEAD box protein 6; ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD) |
| UniProt Protein Name: | Probable ATP-dependent RNA helicase DDX6 |
| UniProt Synonym Protein Names: | ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK |
| UniProt Gene Name: | DDX6 |
| UniProt Entry Name: | DDX6_HUMAN |
