Description
| 抗体名: | DDX43 Antibody (PACO16169) |
| 抗体コード: | PACO16169 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Fusion protein of human DDX43 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16169(DDX43 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cells, Primary antibody: PACO16169(DDX43 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16169(DDX43 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| バックグラウンド: | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid, protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis. |
| シノニム: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| UniProt Protein Function: | DDX43: is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); EC 3.6.4.13; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 6q13 Cellular Component: intracellular Molecular Function:ATP-dependent RNA helicase activity Biological Process: RNA secondary structure unwinding |
| NCBI Summary: | The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NXZ2 |
| NCBI GenInfo Identifier: | 222352149 |
| NCBI Gene ID: | 55510 |
| NCBI Accession: | NP_061135.2 |
| UniProt Secondary Accession: | Q9NXZ2,Q6NXR1, B4E0C8, |
| UniProt Related Accession: | Q9NXZ2 |
| Molecular Weight: | 21,295 Da |
| NCBI Full Name: | probable ATP-dependent RNA helicase DDX43 |
| NCBI Synonym Full Names: | DEAD-box helicase 43 |
| NCBI Official Symbol: | DDX43 |
| NCBI Official Synonym Symbols: | CT13; HAGE |
| NCBI Protein Information: | probable ATP-dependent RNA helicase DDX43 |
| UniProt Protein Name: | Probable ATP-dependent RNA helicase DDX43 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 13; CT13; DEAD box protein 43; DEAD box protein HAGE; Helical antigen |
| Protein Family: | Probable ATP-dependent RNA helicase |
| UniProt Gene Name: | DDX43 |
