Description
| 抗体名: | CYC1 Antibody (PACO22742) |
| 抗体コード: | PACO22742 |
| サイズ: | 100ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| 反応性: | Human |
| 免疫原: | Synthesized peptide derived from internal of human CYC1. |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HepG2 cells, using CYC1 antibody. |
| バックグラウンド: | This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. |
| シノニム: | CY1; cytochrome c-1; cytochrome c1 heme protein; mitochondrial; |
| UniProt Protein Function: | CYC1: This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. Belongs to the cytochrome c family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: membrane; mitochondrial inner membrane; mitochondrion; nucleus Molecular Function:electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity Biological Process: mitochondrial electron transport, ubiquinol to cytochrome c Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 6 |
| NCBI Summary: | This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013] |
| UniProt Code: | P08574 |
| NCBI GenInfo Identifier: | 311033458 |
| NCBI Gene ID: | 1537 |
| NCBI Accession: | P08574.3 |
| UniProt Secondary Accession: | P08574,Q5U062, Q6FHS7, |
| UniProt Related Accession: | P08574 |
| Molecular Weight: | 35,422 Da |
| NCBI Full Name: | Cytochrome c1, heme protein, mitochondrial |
| NCBI Synonym Full Names: | cytochrome c1 |
| NCBI Official Symbol: | CYC1 |
| NCBI Official Synonym Symbols: | UQCR4; MC3DN6 |
| NCBI Protein Information: | cytochrome c1, heme protein, mitochondrial |
| UniProt Protein Name: | Cytochrome c1, heme protein, mitochondrial |
| UniProt Synonym Protein Names: | Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; Cytochrome c-1 |
| Protein Family: | Cytochrome |
| UniProt Gene Name: | CYC1 |
| UniProt Entry Name: | CY1_HUMAN |
