| UniProt Protein Function: | CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular space; extracellular region; external side of plasma membrane Molecular Function:protein binding; CXCR3 chemokine receptor binding; chemokine activity; cytokine activity Biological Process: positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; defense response; positive regulation of cAMP metabolic process; signal transduction; chemotaxis; positive regulation of myoblast differentiation; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; cell-cell signaling; cellular defense response; immune response; positive regulation of release of sequestered calcium ion into cytosol; inflammatory response; defense response to virus |
| NCBI Summary: | This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014] |
| UniProt Code: | Q07325 |
| NCBI GenInfo Identifier: | 585487 |
| NCBI Gene ID: | 4283 |
| NCBI Accession: | Q07325.1 |
| UniProt Secondary Accession: | Q07325,Q503B4, |
| UniProt Related Accession: | Q07325 |
| Molecular Weight: | Approximately 150 kDa |
| NCBI Full Name: | C-X-C motif chemokine 9 |
| NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 9 |
| NCBI Official Symbol: | CXCL9 |
| NCBI Official Synonym Symbols: | CMK; MIG; Humig; SCYB9; crg-10 |
| NCBI Protein Information: | C-X-C motif chemokine 9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma |
| UniProt Protein Name: | C-X-C motif chemokine 9 |
| UniProt Synonym Protein Names: | Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9 |
| Protein Family: | Migration and invasion enhancer |
| UniProt Gene Name: | CXCL9 |
| UniProt Entry Name: | CXCL9_HUMAN |
