Description
| 抗体名: | CWC22 Antibody (PACO47110) |
| 抗体コード: | PACO47110 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Pre-mRNA-splicing factor CWC22 homolog protein (360-623AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO47110 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO47110 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| バックグラウンド: | Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. |
| シノニム: | Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb), CWC22, KIAA1604 NCM |
| UniProt Protein Function: | NCM: a component of the spliceosome C complex. |
| UniProt Protein Details: | Protein type:RNA processing; RNA splicing; Spliceosome Chromosomal Location of Human Ortholog: 2q31.3 Cellular Component: cytoplasm; Golgi apparatus; nuclear speck; nucleoplasm; spliceosome Molecular Function:protein binding; RNA binding Biological Process: nuclear mRNA splicing, via spliceosome; regulation of nuclear mRNA splicing, via spliceosome |
| UniProt Code: | Q9HCG8 |
| NCBI GenInfo Identifier: | 296439380 |
| NCBI Gene ID: | 57703 |
| NCBI Accession: | Q9HCG8.3 |
| UniProt Secondary Accession: | Q9HCG8,Q05DC2, Q4G135, Q52LF0, Q6PEX2, Q7Z6I0, Q9H5L3 Q9H6Q6, |
| UniProt Related Accession: | Q9HCG8 |
| Molecular Weight: | 105,466 Da |
| NCBI Full Name: | Pre-mRNA-splicing factor CWC22 homolog |
| NCBI Synonym Full Names: | CWC22 homolog, spliceosome-associated protein |
| NCBI Official Symbol: | CWC22 |
| NCBI Official Synonym Symbols: | NCM; fSAPb; EIF4GL |
| NCBI Protein Information: | pre-mRNA-splicing factor CWC22 homolog |
| UniProt Protein Name: | Pre-mRNA-splicing factor CWC22 homolog |
| UniProt Synonym Protein Names: | Nucampholin homolog; fSAPb |
| Protein Family: | Pre-mRNA-splicing factor |
| UniProt Gene Name: | CWC22 |
| UniProt Entry Name: | CWC22_HUMAN |
| Antibodies |
| Anti-CWC22 Antibody (CAB13116) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
