Description
| 抗体名: | CSTF2 Antibody (PACO23219) |
| 抗体コード: | PACO23219 |
| サイズ: | 100ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
| 反応性: | Human, Mouse |
| 免疫原: | Synthesized peptide derived from N-terminal of human CSTF2. |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from 293 cells. HepG2 cells and Jurkat cells, using CSTF2 antibody. |
 | Immunofluorescence analysis of HeLa cells, using CSTF2 antibody. |
| バックグラウンド: | One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs By similarity. |
| シノニム: | CF-1 64 kDa; CSTF 64 kDa; CstF-64; cleavage stimulation factor subunit 2; cleavage stimulation factor |
| UniProt Protein Function: | CSTF2: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: Xq22.1 Cellular Component: mRNA cleavage and polyadenylation specificity factor complex; nucleoplasm; nucleus Molecular Function:mRNA binding; protein binding; RNA binding Biological Process: mRNA 3'-end processing; mRNA cleavage; nuclear mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; tRNA splicing |
| NCBI Summary: | This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P33240 |
| NCBI GenInfo Identifier: | 461847 |
| NCBI Gene ID: | 1478 |
| NCBI Accession: | P33240.1 |
| UniProt Secondary Accession: | P33240,Q5H951, Q6LA74, Q8N502, |
| UniProt Related Accession: | P33240 |
| Molecular Weight: | 59,251 Da |
| NCBI Full Name: | Cleavage stimulation factor subunit 2 |
| NCBI Synonym Full Names: | cleavage stimulation factor subunit 2 |
| NCBI Official Symbol: | CSTF2 |
| NCBI Official Synonym Symbols: | CstF-64 |
| NCBI Protein Information: | cleavage stimulation factor subunit 2 |
| UniProt Protein Name: | Cleavage stimulation factor subunit 2 |
| UniProt Synonym Protein Names: | CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; CSTF 64 kDa subunit; CstF-64 |
| Protein Family: | Cleavage stimulation factor |
| UniProt Gene Name: | CSTF2 |
| UniProt Entry Name: | CSTF2_HUMAN |
