Description
| 抗体名: | Cobra venom factor Antibody, FITC conjugated (PACO50936) |
| 抗体コード: | PACO50936 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Naja kaouthia |
| 免疫原: | Recombinant Naja kaouthia Cobra venom factor protein (733-984AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity. |
| シノニム: | Cobra venom factor (CVF) (CVFk) (Complement C3 homolog) [Cleaved into: Cobra venom factor α chain; Cobra venom factor γ chain; Cobra venom factor β chain] |
| UniProt Protein Function: | Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q91132 |
| NCBI GenInfo Identifier: | 54035743 |
| NCBI Gene ID: | |
| NCBI Accession: | Q91132.1 |
| UniProt Secondary Accession: | Q91132,Q6PQH3, Q6RHR7 |
| UniProt Related Accession: | Q91132 |
| Molecular Weight: | 44.4 kDa |
| NCBI Full Name: | Cobra venom factor |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Cobra venom factor |
| UniProt Synonym Protein Names: | Complement C3 homolog |
| Protein Family: | Cobra venom factor |
| UniProt Gene Name: | CVF |
| UniProt Entry Name: | VCO3_NAJKA |
