| UniProt Protein Function: | CNTN6: Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. Belongs to the immunoglobulin superfamily. Contactin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, GPI anchor; Cell adhesion Chromosomal Location of Human Ortholog: 3p26.3 Cellular Component: plasma membrane Biological Process: axon guidance; Notch signaling pathway; central nervous system development; cell adhesion |
| NCBI Summary: | The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UQ52 |
| NCBI GenInfo Identifier: | 7657361 |
| NCBI Gene ID: | 27255 |
| NCBI Accession: | NP_055276.1 |
| UniProt Secondary Accession: | Q9UQ52,Q2KHM2, |
| UniProt Related Accession: | Q9UQ52 |
| Molecular Weight: | 113,956 Da |
| NCBI Full Name: | contactin-6 |
| NCBI Synonym Full Names: | contactin 6 |
| NCBI Official Symbol: | CNTN6 |
| NCBI Official Synonym Symbols: | NB3 |
| NCBI Protein Information: | contactin-6; neural adhesion molecule; neural recognition molecule NB-3 |
| UniProt Protein Name: | Contactin-6 |
| UniProt Synonym Protein Names: | Neural recognition molecule NB-3 |
| Protein Family: | Contactin |
| UniProt Gene Name: | CNTN6 |
| UniProt Entry Name: | CNTN6_HUMAN |
