Description
| 抗体名: | CNKSR2 Antibody |
| 抗体コード: | PACO02730 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human CNK2. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | CNKSR2; CNK2; KIAA0902; KSR2; Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; CNK homolog protein 2; CNK2 |
| UniProt Protein Function: | CNKSR2: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: Xp22.12 Cellular Component: Golgi apparatus; postsynaptic membrane; neuron projection; cell soma; plasma membrane Molecular Function:identical protein binding Biological Process: regulation of signal transduction |
| NCBI Summary: | This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q8WXI2 |
| NCBI GenInfo Identifier: | 281306725 |
| NCBI Gene ID: | 22866 |
| NCBI Accession: | NP_001162118.1 |
| UniProt Related Accession: | Q8WXI2 |
| Molecular Weight: | |
| NCBI Full Name: | connector enhancer of kinase suppressor of ras 2 isoform 2 |
| NCBI Synonym Full Names: | connector enhancer of kinase suppressor of Ras 2 |
| NCBI Official Symbol: | CNKSR2 |
| NCBI Official Synonym Symbols: | CNK2; KSR2; MAGUIN; MRXSHG |
| NCBI Protein Information: | connector enhancer of kinase suppressor of ras 2 |
| UniProt Protein Name: | Connector enhancer of kinase suppressor of ras 2 |
| UniProt Synonym Protein Names: | CNK homolog protein 2 |
| UniProt Gene Name: | CNKSR2 |
| UniProt Entry Name: | CNKR2_HUMAN |
