Description
| 抗体名: | CLDN5 Antibody (PACO05217) |
| 抗体コード: | PACO05217 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:5000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from human Claudin-5 around the non-phosphorylation site of Y217. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF |
| UniProt Protein Function: | Claudin-5: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q11.21 Cellular Component: apicolateral plasma membrane; cortical actin cytoskeleton; integral to membrane; intercellular junction; plasma membrane; tight junction Molecular Function:identical protein binding Biological Process: calcium-independent cell-cell adhesion; intercellular junction assembly; learning; palate development; transforming growth factor beta receptor signaling pathway |
| NCBI Summary: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008] |
| UniProt Code: | O00501 |
| NCBI GenInfo Identifier: | 6685271 |
| NCBI Gene ID: | 7122 |
| NCBI Accession: | O00501.1 |
| UniProt Secondary Accession: | O00501,Q53XW2, Q8WUW3, B3KS11, |
| UniProt Related Accession: | O00501 |
| Molecular Weight: | 23kDa |
| NCBI Full Name: | Claudin-5 |
| NCBI Synonym Full Names: | claudin 5 |
| NCBI Official Symbol: | CLDN5 |
| NCBI Official Synonym Symbols: | AWAL; BEC1; TMVCF; CPETRL1 |
| NCBI Protein Information: | claudin-5 |
| UniProt Protein Name: | Claudin-5 |
| UniProt Synonym Protein Names: | Transmembrane protein deleted in VCFS; TMDVCF |
| Protein Family: | Claudin |
| UniProt Gene Name: | CLDN5 |
