Description
| 抗体名: | CEP55 Antibody (PACO16015) |
| 抗体コード: | PACO16015 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Fusion protein of human CEP55 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse intestinum tenue tissue, human colon cancer tissue, Human testis tissue, Primary antibody: PACO16015(CEP55 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
| バックグラウンド: | Centrosomal protein of 55 kDa is a protein that in humans is encoded by the CEP55 gene. CEP55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division. Interacts (phosphorylated on Ser-425 and Ser-428) with PLK1. Interacts with AKAP9; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PCNT; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PDCD6IP; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry; PDCD6IP competes with TSG101 for the same binding site. |
| シノニム: | centrosomal protein 55kDa |
| UniProt Protein Function: | CEP55: Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); Cell cycle regulation Chromosomal Location of Human Ortholog: 10q23.33 Cellular Component: centrosome; membrane; midbody Molecular Function:protein binding Biological Process: cell separation during cytokinesis; cytokinesis after mitosis; establishment of protein localization; mitotic metaphase plate congression; nuclear organization and biogenesis |
| UniProt Code: | Q53EZ4 |
| NCBI GenInfo Identifier: | 296439403 |
| NCBI Gene ID: | 55165 |
| NCBI Accession: | Q53EZ4.3 |
| UniProt Secondary Accession: | Q53EZ4,Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7 B2RDG8, |
| UniProt Related Accession: | Q53EZ4 |
| Molecular Weight: | 46,857 Da |
| NCBI Full Name: | Centrosomal protein of 55 kDa |
| NCBI Synonym Full Names: | centrosomal protein 55 |
| NCBI Official Symbol: | CEP55 |
| NCBI Official Synonym Symbols: | CT111; URCC6; C10orf3 |
| NCBI Protein Information: | centrosomal protein of 55 kDa |
| UniProt Protein Name: | Centrosomal protein of 55 kDa |
| UniProt Synonym Protein Names: | Up-regulated in colon cancer 6 |
| Protein Family: | Centrosomal protein |
| UniProt Gene Name: | CEP55 |
| UniProt Entry Name: | CEP55_HUMAN |
| Antibodies |
| Anti-CEP55 Antibody (CAB8229) |
| CEP55 Antibody (PACO00583) |
| Phospho-CEP55 (S425) Antibody (PACO04687) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
