Description
| 抗体名: | CENPC Antibody (PACO08362) |
| 抗体コード: | PACO08362 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Human CENPC1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | centromere protein C 1;CENPC1;CENP-C;CENPC;MIF2;hcp-4 ; |
| UniProt Protein Function: | CENPC1: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. Belongs to the CENPC family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q13.2 Cellular Component: centric heterochromatin; condensed nuclear chromosome, pericentric region; cytoplasm; cytosol; kinetochore; nucleoplasm; nucleus Molecular Function:DNA binding Biological Process: chromosome segregation; DNA replication-independent nucleosome assembly at centromere; kinetochore assembly; mitotic cell cycle; sister chromatid cohesion |
| NCBI Summary: | Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q03188 |
| NCBI GenInfo Identifier: | 296434446 |
| NCBI Gene ID: | 1060 |
| NCBI Accession: | Q03188.2 |
| UniProt Secondary Accession: | Q03188,Q6PIR0, Q8IW27, Q9P0M5, |
| UniProt Related Accession: | Q03188 |
| Molecular Weight: | 61,544 Da |
| NCBI Full Name: | Centromere protein C |
| NCBI Synonym Full Names: | centromere protein C |
| NCBI Official Symbol: | CENPC |
| NCBI Official Synonym Symbols: | MIF2; hcp-4; CENP-C; CENPC1 |
| NCBI Protein Information: | centromere protein C |
| UniProt Protein Name: | Centromere protein C |
| UniProt Synonym Protein Names: | Centromere autoantigen C; Centromere protein C 1; CENP-C 1; Interphase centromere complex protein 7 |
| Protein Family: | Centromere protein |
| UniProt Gene Name: | CENPC |
| UniProt Entry Name: | CENPC_HUMAN |
