Description
| 抗体名: | CDCA7L Antibody (PACO58404) |
| 抗体コード: | PACO58404 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Cell division cycle-associated 7-like protein (14-167AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58404 diluted at 1:400 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO58404 diluted at 1:400 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| バックグラウンド: | Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. |
| シノニム: | Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2), CDCA7L, HR1 JPO2 R1 |
| UniProt Protein Function: | Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. |
| UniProt Code: | Q96GN5 |
| NCBI GenInfo Identifier: | 188497635 |
| NCBI Gene ID: | 55536 |
| NCBI Accession: | NP_001120842.1 |
| UniProt Secondary Accession: | Q96GN5,Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2 A4D141, A6NF50, B3KTR5, B4DUT3, C9K0Y1, |
| UniProt Related Accession: | Q96GN5 |
| Molecular Weight: | 49 |
| NCBI Full Name: | cell division cycle-associated 7-like protein isoform 2 |
| NCBI Synonym Full Names: | cell division cycle associated 7 like |
| NCBI Official Symbol: | CDCA7L |
| NCBI Official Synonym Symbols: | R1; JPO2; RAM2 |
| NCBI Protein Information: | cell division cycle-associated 7-like protein |
| UniProt Protein Name: | Cell division cycle-associated 7-like protein |
| UniProt Synonym Protein Names: | Protein JPO2; Transcription factor RAM2 |
| UniProt Gene Name: | CDCA7L |
| Antibodies |
| Anti-CDCA7L Antibody (CAB15472) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
