Description
| 抗体名: | CDC34 Antibody |
| 抗体コード: | PACO00569 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human Cdc34. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | CDC34; UBCH3; UBE2R1; Ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; Ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1 |
| UniProt Protein Function: | CDC34: a member of the ubiquitin-conjugating enzyme family. Is a part of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for ubiquitin-mediated degradation of cell cycle G1 regulators. Required for the initiation of DNA replication. |
| UniProt Protein Details: | Protein type:Ligase; Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:ATP binding; protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity Biological Process: DNA replication initiation; G1/S transition of mitotic cell cycle; positive regulation of neuron apoptosis; proteasomal ubiquitin-dependent protein catabolic process; protein modification process; protein polyubiquitination; protein ubiquitination |
| NCBI Summary: | The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P49427 |
| NCBI GenInfo Identifier: | 2507505 |
| NCBI Gene ID: | 997 |
| NCBI Accession: | P49427.2 |
| UniProt Secondary Accession: | P49427,A8K689, |
| UniProt Related Accession: | P49427 |
| Molecular Weight: | 26,737 Da |
| NCBI Full Name: | Ubiquitin-conjugating enzyme E2 R1 |
| NCBI Synonym Full Names: | cell division cycle 34 |
| NCBI Official Symbol: | CDC34 |
| NCBI Official Synonym Symbols: | UBC3; UBCH3; UBE2R1; E2-CDC34 |
| NCBI Protein Information: | ubiquitin-conjugating enzyme E2 R1 |
| UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 R1 |
| UniProt Synonym Protein Names: | (E3-independent) E2 ubiquitin-conjugating enzyme R1 (EC:2.3.2.24 |
| Protein Family: | Ubiquitin-conjugating enzyme |
| UniProt Gene Name: | CDC34 |
| UniProt Entry Name: | UB2R1_HUMAN |
