Description
| 抗体名: | CD300LB Antibody, Biotin conjugated (PACO25595) |
| 抗体コード: | PACO25595 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human CMRF35-like molecule 7 protein (18-151AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. |
| シノニム: | CMRF35-like molecule 7 (CLM-7) (CD300 antigen-like family member B) (CMRF35-A2) (Immune receptor expressed on myeloid cells 3) (IREM-3) (Leukocyte mono-Ig-like receptor 5) (Triggering receptor expressed on myeloid cells 5) (TREM-5) (CD antigen CD300b), CD300LB, CD300B CLM7 CMRF35A2 IREM3 LMIR5 TREM5 |
| UniProt Protein Function: | Function: Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. Ref.1 Ref.9 |
| UniProt Protein Details: | Subunit structure: Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN. Ref.1 Ref.9 Subcellular location: Cell membrane; Single-pass type I membrane protein By similarity. Tissue specificity: Expressed exclusively in myeloid lineages. Ref.1 Post-translational modification: Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2. Sequence similarities: Belongs to the CD300 family.Contains 1 Ig-like V-type (immunoglobulin-like) domain. Sequence caution: The sequence AAH28091.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence BAF83614.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence EAW89170.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. |
| NCBI Summary: | CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | A8K4G0 |
| NCBI GenInfo Identifier: | 510936990 |
| NCBI Gene ID: | 124599 |
| NCBI Accession: | NP_777552.3 |
| UniProt Secondary Accession: | A8K4G0,Q1EG73, Q8IX40, Q8N6D1, |
| UniProt Related Accession: | A8K4G0 |
| Molecular Weight: | 22,689 Da |
| NCBI Full Name: | CMRF35-like molecule 7 |
| NCBI Synonym Full Names: | CD300 molecule-like family member b |
| NCBI Official Symbol: | CD300LB |
| NCBI Official Synonym Symbols: | CLM7; CLM-7; IREM3; TREM5; CD300b; IREM-3; TREM-5; CMRF35-A2 |
| NCBI Protein Information: | CMRF35-like molecule 7; leukocyte mono-Ig-like receptor 5; CD300 antigen like family member B; immune receptor expressed on myeloid cells 3; triggering receptor expressed on myeloid cells 5 |
| UniProt Protein Name: | CMRF35-like molecule 7 |
| UniProt Synonym Protein Names: | CD300 antigen-like family member B; CMRF35-A2; Immune receptor expressed on myeloid cells 3; IREM-3; Leukocyte mono-Ig-like receptor 5; Triggering receptor expressed on myeloid cells 5 |
| Protein Family: | CMRF35-like molecule |
| UniProt Gene Name: | CD300LB |
| UniProt Entry Name: | CLM7_HUMAN |
