Description
| 抗体名: | CD2BP2 Antibody |
| 抗体コード: | PACO00555 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Monkey |
| 免疫原: | synthesized peptide derived from the Internal region of human CD2BP2. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2 |
| UniProt Protein Function: | CD2BP2: Binds the cytoplasmic domain of CD2 through the GYF domain. |
| UniProt Protein Details: | Protein type:RNA processing; Adaptor/scaffold; Spliceosome Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cytoplasm; nuclear speck; nucleoplasm; nucleus; snRNP U5; U4/U6 x U5 tri-snRNP complex Molecular Function:protein binding; ribonucleoprotein binding Biological Process: nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008] |
| UniProt Code: | O95400 |
| NCBI GenInfo Identifier: | 31339956 |
| NCBI Gene ID: | 10421 |
| NCBI Accession: | O95400.1 |
| UniProt Secondary Accession: | O95400,Q9ULP2, B2RDX2, |
| UniProt Related Accession: | O95400 |
| Molecular Weight: | 37,646 Da |
| NCBI Full Name: | CD2 antigen cytoplasmic tail-binding protein 2 |
| NCBI Synonym Full Names: | CD2 cytoplasmic tail binding protein 2 |
| NCBI Official Symbol: | CD2BP2 |
| NCBI Official Synonym Symbols: | LIN1; Snu40; FWP010; U5-52K; PPP1R59 |
| NCBI Protein Information: | CD2 antigen cytoplasmic tail-binding protein 2 |
| UniProt Protein Name: | CD2 antigen cytoplasmic tail-binding protein 2 |
| UniProt Synonym Protein Names: | U5 snRNP 52K protein; U5-52K |
| Protein Family: | CD2 antigen cytoplasmic tail-binding protein |
| UniProt Gene Name: | CD2BP2 |
| UniProt Entry Name: | CD2B2_HUMAN |