Description
| 抗体名: | CD226 Antibody (PACO18683) |
| 抗体コード: | PACO18683 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Synthetic peptide of human CD226 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18683(CD226 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18683(CD226 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
| バックグラウンド: | This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. |
| シノニム: | CD226 molecule |
| UniProt Protein Function: | DNAM-1: Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion Chromosomal Location of Human Ortholog: 18q22.3 Cellular Component: cell surface; integral to plasma membrane; plasma membrane; external side of plasma membrane; lipid raft Molecular Function:integrin binding; protein binding; cell adhesion molecule binding; protein kinase binding Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; cytokine production; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; cell adhesion; signal transduction; positive regulation of mast cell activation |
| NCBI Summary: | This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15762 |
| NCBI GenInfo Identifier: | 317373338 |
| NCBI Gene ID: | 10666 |
| NCBI Accession: | Q15762.2 |
| UniProt Secondary Accession: | Q15762,B2R818, |
| UniProt Related Accession: | Q15762 |
| Molecular Weight: | |
| NCBI Full Name: | CD226 antigen |
| NCBI Synonym Full Names: | CD226 molecule |
| NCBI Official Symbol: | CD226 |
| NCBI Official Synonym Symbols: | PTA1; DNAM1; DNAM-1; TLiSA1 |
| NCBI Protein Information: | CD226 antigen; adhesion glycoprotein; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen |
| UniProt Protein Name: | CD226 antigen |
| UniProt Synonym Protein Names: | DNAX accessory molecule 1 |
| Protein Family: | CD226 antigen |
| UniProt Gene Name: | CD226 |
| UniProt Entry Name: | CD226_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
