Description
| 抗体名: | CACNB1 Antibody (PACO08135) |
| 抗体コード: | PACO08135 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human CACNB1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | calcium channel, voltage-dependent, β 1 subunit;CACNB1;CAB1;CACNLB1;CCHLB1;MGC41896 ; |
| UniProt Protein Function: | CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Channel, calcium Chromosomal Location of Human Ortholog: 17q21-q22 Cellular Component: sarcoplasmic reticulum; T-tubule; voltage-gated calcium channel complex Molecular Function:voltage-gated calcium channel activity; high voltage-gated calcium channel activity Biological Process: synaptic transmission; axon guidance; transport; protein targeting to membrane; neuromuscular junction development |
| NCBI Summary: | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q02641 |
| NCBI GenInfo Identifier: | 20455481 |
| NCBI Gene ID: | 782 |
| NCBI Accession: | Q02641.3 |
| UniProt Related Accession: | Q02641 |
| Molecular Weight: | 57kDa |
| NCBI Full Name: | Voltage-dependent L-type calcium channel subunit beta-1 |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit beta 1 |
| NCBI Official Symbol: | CACNB1 |
| NCBI Official Synonym Symbols: | CAB1; CCHLB1; CACNLB1 |
| NCBI Protein Information: | voltage-dependent L-type calcium channel subunit beta-1 |
| UniProt Protein Name: | Voltage-dependent L-type calcium channel subunit beta-1 |
| UniProt Synonym Protein Names: | Calcium channel voltage-dependent subunit beta 1 |
| Protein Family: | Voltage-dependent L-type calcium channel |
| UniProt Gene Name: | CACNB1 |
| UniProt Entry Name: | CACB1_HUMAN |
