| UniProt Protein Function: | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. |
| NCBI Summary: | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q10588 |
| NCBI GenInfo Identifier: | 116241273 |
| NCBI Gene ID: | 683 |
| NCBI Accession: | Q10588.2 |
| UniProt Secondary Accession: | Q10588,Q1XII0, Q5U0K0, Q96EN3, B2R6A2, |
| UniProt Related Accession: | Q10588 |
| Molecular Weight: | 29,326 Da |
| NCBI Full Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
| NCBI Synonym Full Names: | bone marrow stromal cell antigen 1 |
| NCBI Official Symbol: | BST1 |
| NCBI Official Synonym Symbols: | CD157 |
| NCBI Protein Information: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
| UniProt Protein Name: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
| UniProt Synonym Protein Names: | ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157 |
| Protein Family: | GPI inositol-deacylase |
| UniProt Gene Name: | BST1 |
