Description
| Product Name: | Bovine BTC Recombinant Protein |
| Product Code: | RPPB0122 |
| Size: | 20µg |
| Species: | Bovine |
| Target: | BTC |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | The Betacellulin Bovine Recombinant was lyophilized after extensive dialysis against 50mM acetic acid. |
| Solubility: | It is recommended to reconstitute the lyophilized BTC Bovine in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Betacellulin Bovine Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BTC Bovine should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first five N-terminal amino acids was determined and was found to be Asp-Gly-Asn-Ser-Thr |
| Biological Activity: | The ED50, calculated by the dose-dependent proliferation of murine BALB\C 3T3 cells (measured by 3H-thymidine uptake) is < 10.0 ng/ml, corresponding to a Specific Activity 100,000 units/mg. |
Btc is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the egf receptor and other related receptors.
Betacellulin Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and having a molecular mass of 9003 Dalton. Betacellulin Bovine Recombinant is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9TTC5 |
| NCBI GenInfo Identifier: | 13626137 |
| NCBI Gene ID: | 280737 |
| NCBI Accession: | Q9TTC5.1 |
| UniProt Secondary Accession: | Q9TTC5 |
| UniProt Related Accession: | Q9TTC5 |
| Molecular Weight: | 19,640 Da |
| NCBI Full Name: | Probetacellulin |
| NCBI Synonym Full Names: | betacellulin< |
| NCBI Official Symbol: | BTC�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | probetacellulin |
| UniProt Protein Name: | Probetacellulin |
| UniProt Synonym Protein Names: | |
| Protein Family: | Probetacellulin |
| UniProt Gene Name: | BTC�� |
| UniProt Entry Name: | BTC_BOVIN |
