Overall, the CD300A Polyclonal Antibody is essential for researchers studying immune regulation and inflammatory responses. With its high reactivity and specificity for CD300A, this antibody provides valuable insights into the role of CD300A in various cellular processes and diseases.
Get your hands on the CD300A Polyclonal Antibody today for groundbreaking research in immunology and cancer biology.
Antibody Name:
botF Antibody (PACO61830)
Antibody SKU:
PACO61830
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Clostridium botulinum
Immunogen:
Recombinant Clostridium botulinum Botulinum neurotoxin type F protein (1-436AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: botF antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa.
Background:
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '58-Gln- |-Lys-59' bond of synaptobrevins-1 and -2.
Synonyms:
Botulinum neurotoxin type F (BoNT/F) (EC 3.4.24.69) (Bontoxilysin-F) [Cleaved into: Botulinum neurotoxin F light chain; Botulinum neurotoxin F heavy chain], botF
UniProt Protein Function:
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '58-Gln-|-Lys-59' bond of synaptobrevins-1 and -2.
