| UniProt Protein Function: | BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Cytokine Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular space Molecular Function:cytokine activity; receptor binding; transforming growth factor beta receptor binding Biological Process: BMP signaling pathway; cell development; cell-cell signaling; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development |
| NCBI Summary: | BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P12645 |
| NCBI GenInfo Identifier: | 215273985 |
| NCBI Gene ID: | 651 |
| NCBI Accession: | P12645.2 |
| UniProt Secondary Accession: | P12645,Q4VAS5, |
| UniProt Related Accession: | P12645 |
| Molecular Weight: | 53,372 Da |
| NCBI Full Name: | Bone morphogenetic protein 3 |
| NCBI Synonym Full Names: | bone morphogenetic protein 3 |
| NCBI Official Symbol: | BMP3 |
| NCBI Official Synonym Symbols: | BMP-3A |
| NCBI Protein Information: | bone morphogenetic protein 3 |
| UniProt Protein Name: | Bone morphogenetic protein 3 |
| UniProt Synonym Protein Names: | Bone morphogenetic protein 3A; BMP-3A; Osteogenin |
| Protein Family: | Bone morphogenetic protein |
| UniProt Gene Name: | BMP3 |
| UniProt Entry Name: | BMP3_HUMAN |
