Description
| 抗体名: | BDKRB1 Antibody |
| 抗体コード: | PACO04973 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | WB:1:500-1:2000, IF:1:200-1:1000 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the Internal region of human Bradykinin B1 R. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor |
| UniProt Protein Function: | BKR1: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation. Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1 Chromosomal Location of Human Ortholog: 14q32.1-q32.2 Cellular Component: endoplasmic reticulum; integral to plasma membrane; plasma membrane Molecular Function:protein binding Biological Process: elevation of cytosolic calcium ion concentration |
| NCBI Summary: | Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| UniProt Code: | P46663 |
| NCBI GenInfo Identifier: | 85681914 |
| NCBI Gene ID: | 623 |
| NCBI Accession: | P46663.3 |
| UniProt Secondary Accession: | P46663,Q546S7, Q8N0Y8, A8K7F5, |
| UniProt Related Accession: | P46663 |
| Molecular Weight: | 40,495 Da |
| NCBI Full Name: | B1 bradykinin receptor |
| NCBI Synonym Full Names: | bradykinin receptor B1 |
| NCBI Official Symbol: | BDKRB1 |
| NCBI Official Synonym Symbols: | B1R; BKR1; B1BKR; BKB1R; BDKRB2; BRADYB1 |
| NCBI Protein Information: | B1 bradykinin receptor |
| UniProt Protein Name: | B1 bradykinin receptor |
| Protein Family: | B1 bradykinin receptor |
| UniProt Gene Name: | BDKRB1 |
| UniProt Entry Name: | BKRB1_HUMAN |
