Description
| 抗体名: | BCAT1 Antibody (PACO07987) |
| 抗体コード: | PACO07987 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human BCAT1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | branched chain aminotransferase 1, cytosolic;BCAT1;BCT1;DKFZp686E12175;ECA39;MECA39;PNAS-121;PP18 ; |
| UniProt Protein Function: | BCAT1: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.6.1.42; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Transferase Chromosomal Location of Human Ortholog: 12p12.1 Cellular Component: mitochondrion; cytosol Molecular Function:identical protein binding; branched-chain-amino-acid transaminase activity Biological Process: cell proliferation; branched chain family amino acid catabolic process; branched chain family amino acid biosynthetic process; G1/S transition of mitotic cell cycle |
| NCBI Summary: | This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] |
| UniProt Code: | P54687 |
| NCBI GenInfo Identifier: | 215274162 |
| NCBI Gene ID: | 586 |
| NCBI Accession: | P54687.3 |
| UniProt Secondary Accession: | P54687,Q68DQ7, Q96MY9, B3KY27, B7Z2M5, B7Z5L0, F5H5E4 |
| UniProt Related Accession: | P54687 |
| Molecular Weight: | 386 |
| NCBI Full Name: | Branched-chain-amino-acid aminotransferase, cytosolic |
| NCBI Synonym Full Names: | branched chain amino-acid transaminase 1, cytosolic |
| NCBI Official Symbol: | BCAT1 |
| NCBI Official Synonym Symbols: | BCT1; PP18; BCATC; ECA39; MECA39; PNAS121 |
| NCBI Protein Information: | branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; branched chain aminotransferase 1, cytosolic |
| UniProt Protein Name: | Branched-chain-amino-acid aminotransferase, cytosolic |
| UniProt Synonym Protein Names: | Protein ECA39 |
| Protein Family: | Branched-chain-amino-acid aminotransferase |
| UniProt Gene Name: | BCAT1 |
| UniProt Entry Name: | BCAT1_HUMAN |
