Description
| 抗体名: | B4GALT3 Antibody (PACO05609) |
| 抗体コード: | PACO05609 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from the Internal region of human β -1,4-Gal-T3. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | B4GALT3; β-1; 4-galactosyltransferase 3; β-1,4-GalTase 3; β4Gal-T3; b4Gal-T3; UDP-Gal:β-GlcNAc β-1,4-galactosyltransferase 3; UDP-galactose:β-N-acetylglucosamine β-1,4-galactosyltransferase 3 |
| UniProt Protein Function: | B4GALT3: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Belongs to the glycosyltransferase 7 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.4.1.38; EC 2.4.1.90; Glycan Metabolism - N-glycan biosynthesis; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 1q23.3 Cellular Component: cytosol; Golgi apparatus; Golgi membrane Molecular Function:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; galactosyltransferase activity Biological Process: keratan sulfate biosynthetic process |
| NCBI Summary: | This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | O60512 |
| NCBI GenInfo Identifier: | 68053339 |
| NCBI Gene ID: | 8703 |
| NCBI Accession: | O60512.2 |
| UniProt Secondary Accession: | O60512,O60910, Q9BPZ4, Q9H8T2, D3DVG3, |
| UniProt Related Accession: | O60512 |
| Molecular Weight: | 44kDa |
| NCBI Full Name: | Beta-1,4-galactosyltransferase 3 |
| NCBI Synonym Full Names: | beta-1,4-galactosyltransferase 3 |
| NCBI Official Symbol: | B4GALT3 |
| NCBI Official Synonym Symbols: | beta4Gal-T3 |
| NCBI Protein Information: | beta-1,4-galactosyltransferase 3 |
| UniProt Protein Name: | Beta-1,4-galactosyltransferase 3 |
| UniProt Synonym Protein Names: | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3Including the following 3 domains:N-acetyllactosamine synthase (EC:2.4.1.90)Alternative name(s):Nal synthase |
| Protein Family: | Beta-1,4-galactosyltransferase |
| UniProt Gene Name: | B4GALT3 |
