Description
| Product Name: | AZGP1 Recombinant Protein |
| Product Code: | RPPB2831 |
| Size: | 20µg |
| Target: | AZGP1 |
| Synonyms: | Zinc-alpha-2-glycoprotein, ZA2G, ZAG, Zn-alpha-2-GP, Zn-alpha-2-glycoprotein. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | AZGP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSQENQDGR YSLTYIYTGL SKHVEDVPAF QALGSLNDLQ FFRYNSKDRKSQPMGLWRQV EGMEDWKQDS QLQKAREDIF METLKDIVEY YNDSNGSHVL QGRFGCEIEN NRSSGAFWKYYYDGKDYIEF NKEIPAWVPF DPAAQITKQK WEAEPVYVQR AKAYLEEECP ATLRKYLKYS KNILDRQDPPSVVVTSHQAP GEKKKLKCLA YDFYPGKIDV HWTRAGEVQE PELRGDVLHN GNGTYQSWVV VAVPPQDTAPYSCHVQHSSL AQPLVVPWEA S |
Zinc-alpha-2-glycoprotein (AZGP1) protein stimulates lipid degradation in adipocytes and causes the massive fat losses linked with various advanced cancers. AZGP1 may bind polyunsaturated fatty acids.
AZGP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 301 amino acids (21-298 a.a) and having a molecular mass of 34.5kDa.AZGP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | AZGP1: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids. Belongs to the MHC class I family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: extracellular space; extracellular region; plasma membrane; nucleus; MHC class I protein complex Molecular Function:peptide antigen binding; protein transmembrane transporter activity; glycoprotein binding; antigen binding; ribonuclease activity Biological Process: retinal homeostasis; antigen processing and presentation; negative regulation of cell proliferation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune response; detection of chemical stimulus involved in sensory perception of bitter taste; cell adhesion |
| UniProt Code: | P25311 |
| NCBI GenInfo Identifier: | 292495049 |
| NCBI Gene ID: | 563 |
| NCBI Accession: | P25311.2 |
| UniProt Secondary Accession: | P25311,O60386, Q5XKQ4, Q8N4N0, D6W5T8, |
| UniProt Related Accession: | P25311 |
| Molecular Weight: | |
| NCBI Full Name: | Zinc-alpha-2-glycoprotein |
| NCBI Synonym Full Names: | alpha-2-glycoprotein 1, zinc-binding |
| NCBI Official Symbol: | AZGP1�� |
| NCBI Official Synonym Symbols: | ZAG; ZA2G�� |
| NCBI Protein Information: | zinc-alpha-2-glycoprotein; zn-alpha-2-GP; Zn-alpha2-glycoprotein; zn-alpha-2-glycoprotein; Alpha-2-glycoprotein, zinc |
| UniProt Protein Name: | Zinc-alpha-2-glycoprotein |
| Protein Family: | Zinc-alpha-2-glycoprotein |
| UniProt Gene Name: | AZGP1�� |
| UniProt Entry Name: | ZA2G_HUMAN |
