Description
| 抗体名: | ATP5I Antibody (PACO22161) |
| 抗体コード: | PACO22161 |
| サイズ: | 100ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| 反応性: | Human |
| 免疫原: | Synthesized peptide derived from C-terminal of human ATP5I. |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO cells, using ATP5I antibody. |
| バックグラウンド: | Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane. |
| シノニム: | ATP synthase e chain; mitochondrial; ATP5K; EC 3.6.3.14; F1F0-ATP synthase |
| UniProt Protein Function: | ATP5I: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. Belongs to the ATPase e subunit family. |
| UniProt Protein Details: | Protein type:EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrion Molecular Function:ATPase activity; hydrogen ion transmembrane transporter activity; transmembrane transporter activity Biological Process: cellular metabolic process; mitochondrial ATP synthesis coupled proton transport |
| NCBI Summary: | Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010] |
| UniProt Code: | P56385 |
| NCBI GenInfo Identifier: | 3023369 |
| NCBI Gene ID: | 521 |
| NCBI Accession: | P56385.2 |
| UniProt Secondary Accession: | P56385,Q0D2L9, |
| UniProt Related Accession: | P56385 |
| Molecular Weight: | 7,933 Da |
| NCBI Full Name: | ATP synthase subunit e, mitochondrial |
| NCBI Synonym Full Names: | ATP synthase, H+ transporting, mitochondrial Fo complex subunit E |
| NCBI Official Symbol: | ATP5I |
| NCBI Official Synonym Symbols: | ATP5K |
| NCBI Protein Information: | ATP synthase subunit e, mitochondrial |
| UniProt Protein Name: | ATP synthase subunit e, mitochondrial |
| Protein Family: | ATP synthase |
| UniProt Gene Name: | ATP5I |
| UniProt Entry Name: | ATP5I_HUMAN |
