Description
| 抗体名: | ATAD3A Antibody (PACO43843) |
| 抗体コード: | PACO43843 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| 反応性: | Human, Mouse |
| 免疫原: | Recombinant Human ATPase family AAA domain-containing protein 3A protein (1-240AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: ATAD3A antibody at 4µg/ml. Lane 1: A549 whole cell lysate. Lane 2: Mouse spleen tissue. Lane 3: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 72, 67, 58 kDa. Observed band size: 72 kDa. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43843 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO43843 at dilution of 1:100. |
| バックグラウンド: | Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. |
| シノニム: | ATPase family AAA domain-containing protein 3A, ATAD3A |
| UniProt Protein Function: | ATAD3A: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 1p36.33 Cellular Component: mitochondrion Biological Process: cell growth; negative regulation of apoptosis |
| NCBI Summary: | ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008] |
| UniProt Code: | Q9NVI7 |
| NCBI GenInfo Identifier: | 84028405 |
| NCBI Gene ID: | 55210 |
| NCBI Accession: | Q9NVI7.2 |
| UniProt Secondary Accession: | Q9NVI7,Q5SV23, Q8N275, Q96A50, B3KPB3, D2K8Q1, G3V1I6 |
| UniProt Related Accession: | Q9NVI7 |
| Molecular Weight: | 57,948 Da |
| NCBI Full Name: | ATPase family AAA domain-containing protein 3A |
| NCBI Synonym Full Names: | ATPase family, AAA domain containing 3A |
| NCBI Official Symbol: | ATAD3A |
| NCBI Protein Information: | ATPase family AAA domain-containing protein 3A |
| UniProt Protein Name: | ATPase family AAA domain-containing protein 3A |
| Protein Family: | ATPase family AAA domain-containing protein |
| UniProt Gene Name: | ATAD3A |
| UniProt Entry Name: | ATD3A_HUMAN |
| Antibodies |
| Anti-ATAD3A Antibody (CAB8230) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
