The ASH2L Rabbit Monoclonal Antibody (CAB4892) is a key tool for researchers studying ASH2L, a crucial protein involved in chromatin remodeling and gene regulation. This high-quality antibody, generated using rabbit monoclonal technology, exhibits exceptional specificity and sensitivity in detecting ASH2L in various experimental settings.ASH2L is known to be a subunit of the SET1/MLL histone methyltransferase complexes, playing a role in epigenetic regulation and transcriptional activation. Dysregulation of ASH2L has been linked to various diseases, including cancer and developmental disorders, making it a promising target for therapeutic interventions.
The ASH2L Rabbit Monoclonal Antibody (CAB4892) is validated for use in techniques such as Western blot, immunofluorescence, and immunohistochemistry, providing researchers with a versatile tool for investigating ASH2L expression and function in different cell types and tissues. With its reliable performance and broad applicability, this antibody is an invaluable asset for studies in epigenetics, gene regulation, and disease mechanisms.
Product Name:
ASH2L Rabbit Monoclonal Antibody
SKU:
CAB4892
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 529-628 of human ASH2L (Q9UBL3).
Enables beta-catenin binding activity and transcription cis-regulatory region binding activity. Contributes to histone methyltransferase activity (H3-K4 specific). Involved in histone H3-K4 methylation; positive regulation of cell population proliferation; and response to estrogen. Acts upstream of or within cellular response to DNA damage stimulus. Located in nucleus. Part of MLL3/4 complex and Set1C/COMPASS complex.
Purification Method:
Affinity purification
Gene ID:
9070
Clone Number:
ARC0326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ASH2L Rabbit mAb (CAB4892) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
