Description
| 抗体名: | ASCC3 Antibody (PACO07879) |
| 抗体コード: | PACO07879 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human ASCC3 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | activating signal cointegrator 1 complex subunit 3;ASCC3;ASC1p200;DJ467N11.1;HELIC1;MGC26074;RNAH;dJ121G13.4 ; |
| UniProt Protein Function: | ASCC3: 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation. Belongs to the helicase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.6.4.12; Helicase; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 6q16 Cellular Component: Golgi apparatus; membrane; cytoplasm; intracellular; nucleus Molecular Function:protein binding; ATP-dependent 3'-5' DNA helicase activity; ATP binding Biological Process: cell proliferation; DNA dealkylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; DNA duplex unwinding |
| NCBI Summary: | This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q8N3C0 |
| NCBI GenInfo Identifier: | 158518649 |
| NCBI Gene ID: | 10973 |
| NCBI Accession: | Q8N3C0.3 |
| UniProt Related Accession: | Q8N3C0 |
| Molecular Weight: | 160kDa |
| NCBI Full Name: | Activating signal cointegrator 1 complex subunit 3 |
| NCBI Synonym Full Names: | activating signal cointegrator 1 complex subunit 3 |
| NCBI Official Symbol: | ASCC3 |
| NCBI Official Synonym Symbols: | RNAH; HELIC1; ASC1p200 |
| NCBI Protein Information: | activating signal cointegrator 1 complex subunit 3 |
| UniProt Protein Name: | Activating signal cointegrator 1 complex subunit 3 |
| UniProt Synonym Protein Names: | ASC-1 complex subunit p200; ASC1p200; Helicase, ATP binding 1; Trip4 complex subunit p200 |
| Protein Family: | Activating signal cointegrator 1 complex |
| UniProt Gene Name: | ASCC3 |
| UniProt Entry Name: | ASCC3_HUMAN |
