Description
| 抗体名: | ARHGEF5 Antibody (PACO05379) |
| 抗体コード: | PACO05379 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:20000, WB:1:500-1:2000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from the Internal region of human Oncogene TIM. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | ARHGEF5; TIM; Rho guanine nucleotide exchange factor 5; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM |
| UniProt Protein Function: | ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis; Oncoprotein Chromosomal Location of Human Ortholog: 7q35 Cellular Component: cytoplasm; nucleoplasm; nucleus; plasma membrane Molecular Function:GTP binding; guanyl-nucleotide exchange factor activity; protein binding Biological Process: positive regulation of JNK activity; positive regulation of stress fiber formation; positive regulation of transcription factor activity; regulation of actin cytoskeleton organization and biogenesis; regulation of cytoskeleton organization and biogenesis; regulation of GTPase activity |
| NCBI Summary: | Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q12774 |
| NCBI GenInfo Identifier: | 290457679 |
| NCBI Gene ID: | 7984 |
| NCBI Accession: | Q12774.3 |
| UniProt Secondary Accession: | Q12774,Q6ZML7, A6NNJ2, |
| UniProt Related Accession: | Q12774 |
| Molecular Weight: | 60,056 Da |
| NCBI Full Name: | Rho guanine nucleotide exchange factor 5 |
| NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor 5 |
| NCBI Official Symbol: | ARHGEF5 |
| NCBI Official Synonym Symbols: | P60; TIM; GEF5; TIM1 |
| NCBI Protein Information: | rho guanine nucleotide exchange factor 5 |
| UniProt Protein Name: | Rho guanine nucleotide exchange factor 5 |
| UniProt Synonym Protein Names: | Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM |
| Protein Family: | Rho guanine nucleotide exchange factor |
| UniProt Gene Name: | ARHGEF5 |
| UniProt Entry Name: | ARHG5_HUMAN |
