Description
| 抗体名: | AP1M1 Antibody (PACO45219) |
| 抗体コード: | PACO45219 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human AP-1 complex subunit mu-1 protein (1-160AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: AP1M1 antibody at 1.43µg/ml. Lane 1: A375 whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: Hela whole cell lysate. Lane 4: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 49, 50 kDa. Observed band size: 49 kDa.. |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO45219 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO45219 at dilution of 1:100. |
| バックグラウンド: | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| シノニム: | AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin), AP1M1, CLTNM |
| UniProt Protein Function: | AP1M1: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Belongs to the adaptor complexes medium subunit family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 19p13.12 Cellular Component: cytoplasmic vesicle membrane; cytosol; Golgi membrane; lysosomal membrane; membrane; trans-Golgi network membrane Molecular Function:protein binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; melanosome organization and biogenesis; regulation of defense response to virus by virus |
| NCBI Summary: | The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BXS5 |
| NCBI GenInfo Identifier: | 18202738 |
| NCBI Gene ID: | 8907 |
| NCBI Accession: | Q9BXS5.3 |
| UniProt Secondary Accession: | Q9BXS5,Q4TTY5, |
| UniProt Related Accession: | Q9BXS5 |
| Molecular Weight: | 49,840 Da |
| NCBI Full Name: | AP-1 complex subunit mu-1 |
| NCBI Synonym Full Names: | adaptor related protein complex 1 mu 1 subunit |
| NCBI Official Symbol: | AP1M1 |
| NCBI Official Synonym Symbols: | AP47; CLTNM; MU-1A; CLAPM2 |
| NCBI Protein Information: | AP-1 complex subunit mu-1 |
| UniProt Protein Name: | AP-1 complex subunit mu-1 |
| UniProt Synonym Protein Names: | AP-mu chain family member mu1A; Adaptor protein complex AP-1 subunit mu-1; Adaptor-related protein complex 1 subunit mu-1; Clathrin assembly protein complex 1 mu-1 medium chain 1; Clathrin coat assembly protein AP47; Clathrin coat-associated protein AP47; Golgi adaptor HA1/AP1 adaptin mu-1 subunit; Mu-adaptin 1; Mu1A-adaptin |
| Protein Family: | AP-1 complex |
| UniProt Gene Name: | AP1M1 |
| UniProt Entry Name: | AP1M1_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
