The TRRAP Polyclonal Antibody (CAB18849) is a versatile tool for researchers investigating the TRRAP protein, a key regulator of gene expression and chromatin remodeling. This antibody, developed in rabbits, shows high specificity and sensitivity in detecting TRRAP in human samples, making it suitable for Western blot analysis.TRRAP plays a crucial role in various cellular processes, including DNA repair, transcriptional regulation, and cell cycle control. Dysregulation of TRRAP has been linked to numerous diseases, such as cancer and neurological disorders, highlighting its importance in biological pathways.
By targeting TRRAP, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.With its ability to accurately detect TRRAP in different cell types, the TRRAP Polyclonal Antibody is an indispensable tool for studies in molecular biology, oncology, and neurobiology. By elucidating the functions of TRRAP, researchers can advance our understanding of complex biological processes and potentially develop innovative treatments for a range of diseases.
Product Name:
TRRAP Rabbit Polyclonal Antibody
SKU:
CAB18849
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 3660-3859 of TRRAP (NP_001231509.1).
This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8295
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRRAP Rabbit pAb (CAB18849) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
