The Anti-TET1 Antibody (CAB20427) is a valuable tool for researchers studying TET1, a key enzyme involved in DNA demethylation and gene regulation. This polyclonal antibody is produced in rabbits and has high reactivity with human samples, making it ideal for use in Western blot applications. By specifically targeting the TET1 protein, this antibody enables the detection and analysis of TET1 expression in various cell types, providing insights into its function in epigenetic processes.TET1 is known for its role in DNA demethylation, which is essential for regulating gene expression and maintaining genomic stability.
Dysregulation of TET1 has been implicated in various diseases, including cancer and neurological disorders. By studying TET1 expression and activity, researchers can uncover new insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets for intervention.Overall, the Anti-TET1 Antibody is a valuable tool for investigating the role of TET1 in epigenetic regulation and disease pathogenesis. Its specificity and reliability make it a crucial asset for researchers in the fields of molecular biology, genetics, and epigenetics.
Product Name:
TET1 Rabbit Polyclonal Antibody
SKU:
CAB20427
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1749-1902 of mouse TET1 (NP_001240786.1).
Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
Purification Method:
Affinity purification
Gene ID:
52463
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human testis using TET1 Rabbit pAb (CAB20427) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
