The Anti-SOX1 Antibody (CAB5949) is a highly specific antibody designed for research involving SOX1, a transcription factor important in neural development and stem cell maintenance. This antibody, generated in rabbits, is suitable for use in a variety of applications including Western blot, immunohistochemistry, and flow cytometry. It binds specifically to the SOX1 protein, allowing for accurate detection and localization in various cell types.SOX1 is a critical transcription factor involved in the regulation of neural stem cells and neural precursor cells, playing a key role in the development and differentiation of the nervous system.
Dysregulation of SOX1 has been implicated in various neurological disorders and cancers, making it a promising target for research in these areas. Studying the role of SOX1 using this antibody can provide valuable insights into its function and potential therapeutic applications in neurobiology and oncology.
Product Name:
SOX1 Rabbit Monoclonal Antibody
SKU:
CAB5949
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOX1 (O00570).
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
Purification Method:
Affinity purification
Gene ID:
6656
Clone Number:
ARC2100
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of A-549, using SOX1 Rabbit mAb (CAB5949) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
