The Anti-S100A8 Antibody (CAB20474) is a valuable tool for researchers studying S100A8, a calcium-binding protein involved in inflammatory responses and immune regulation. This polyclonal antibody, produced in rabbits, is highly specific for detecting S100A8 in human samples and is validated for use in Western blot applications.S100A8, also known as calgranulin A, plays a key role in promoting inflammation and is often found in elevated levels in various inflammatory conditions, making it a potential biomarker for disease diagnosis and prognosis. By targeting S100A8 with this antibody, researchers can accurately detect and analyze its expression in different cell types, providing insights into its functions and potential as a therapeutic target in inflammatory diseases and cancer research.
The Anti-S100A8 Antibody is a reliable tool for investigating the role of S100A8 in immune responses, inflammation, and disease pathogenesis. Its high specificity and sensitivity make it an ideal choice for researchers looking to explore the molecular mechanisms underlying inflammatory processes and develop targeted interventions for related disorders.
Product Name:
S100A8 Rabbit Polyclonal Antibody
SKU:
CAB20474
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of mouse S100A8 (NP_038678.1).
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Acts upstream of or within astrocyte development and positive regulation of peptide secretion. Predicted to be located in cytosol and intermediate filament cytoskeleton. Predicted to be active in extracellular space. Is expressed in several structures, including bone marrow; extraembryonic component; female reproductive system; and liver. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8).
Purification Method:
Affinity purification
Gene ID:
20201
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using S100A8 Rabbit pAb (CAB20474) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
