The Anti-S100A8 Antibody (CAB12018) is a powerful tool for researchers studying S100A8, a calcium-binding protein involved in inflammatory responses and immune regulation. This polyclonal antibody is produced in rabbits and has been shown to be highly specific and reactive in human samples, making it an excellent choice for studies in immunology and inflammation.S100A8 is a key player in the immune response, activating inflammatory pathways and promoting tissue damage in various diseases, including cancer and inflammatory disorders. By targeting and detecting S100A8 with this antibody, researchers can gain valuable insights into the role of this protein in disease progression and potentially identify new therapeutic targets.
Validated for use in Western blot applications, the Anti-S100A8 Antibody provides researchers with a reliable tool for analyzing S100A8 expression in different cell types and tissues. Its high specificity and sensitivity make it a valuable asset in the quest to better understand the mechanisms underlying inflammation and immune dysregulation.
Product Name:
MRP8 Rabbit Monoclonal Antibody
SKU:
CAB12018
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-93 of human S100A8 (P05109).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6279
Clone Number:
ARC0478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse spleen cells, using S100A8 antibody (CAB12018) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
