The RBCK1 Polyclonal Antibody (CAB20468) is a valuable tool for researchers studying RBCK1, a protein involved in regulating various cellular processes including protein degradation and immune response. This antibody, produced in rabbits, has high reactivity towards human RBCK1 samples and is validated for use in Western blot applications. By binding specifically to the RBCK1 protein, this antibody enables accurate detection and analysis in a variety of cell types.RBCK1, also known as hRMA1, is a key player in the ubiquitin-proteasome system, where it acts as an E3 ubiquitin ligase to target proteins for degradation.
In addition, RBCK1 is involved in immune signaling pathways, making it a potential target for research in autoimmune diseases, infectious diseases, and cancer. Understanding the role of RBCK1 in these processes is essential for developing therapeutic interventions that target protein degradation and immune response modulation.Overall, the RBCK1 Polyclonal Antibody (CAB20468) offers researchers a reliable tool for investigating the functions of RBCK1 in various physiological and pathological conditions, providing insights that could contribute to the development of novel treatment strategies for a range of diseases.
Product Name:
RBCK1 Rabbit Polyclonal Antibody
SKU:
CAB20468
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-192 of human RBCK1 (NP_112506.2).
Enables several functions, including identical protein binding activity; protein sequestering activity; and ubiquitin binding activity. Involved in several processes, including T cell receptor signaling pathway; cellular protein metabolic process; and regulation of DNA-binding transcription factor activity. Part of LUBAC complex. Implicated in glycogen storage disease.
Purification Method:
Affinity purification
Gene ID:
10616
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RBCK1 antibody (CAB20468) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
