The Anti-PAK3 Antibody (CAB3363) is a valuable tool for researchers studying the P21-activated kinase 3 (PAK3) protein, a key regulator of cell growth, differentiation, and cytoskeleton dynamics. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.PAK3 is a critical player in signal transduction pathways that control cell morphology and motility, making it a compelling target for investigations into cancer biology, neurodevelopmental disorders, and other conditions involving aberrant cell signaling.
The Anti-PAK3 Antibody enables researchers to detect and analyze PAK3 expression in a variety of cell types, providing insights into its function and potential therapeutic implications.By understanding the role of PAK3 in cellular processes, researchers can further elucidate its involvement in disease pathogenesis and identify novel therapeutic strategies that target PAK3 signaling pathways. The Anti-PAK3 Antibody is a valuable tool for advancing research in molecular biology, cancer biology, and neurobiology.
Product Name:
PAK3 Rabbit Monoclonal Antibody
SKU:
CAB3363
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAK3 (O75914).
cytoplasm, cytosol, endosome, glutamatergic synapse, plasma membrane, postsynaptic density
Calculated MW:
62kDa
Observed MW:
65kDa
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
5063
Clone Number:
ARC1955
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PAK3 Rabbit mAb (CAB3363) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
