The p70 S6 Kinase 2 Polyclonal Antibody (CAB9100) is a valuable tool for research focused on the p70 S6 kinase 2 protein, an important regulator of cell growth and protein synthesis. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the p70 S6 kinase 2 protein, this antibody enables the detection and analysis of this critical signaling molecule in a variety of cell types, making it an excellent choice for studies in the fields of molecular biology and cancer research.p70 S6 kinase 2 plays a key role in the regulation of cell growth, cell proliferation, and protein synthesis in response to various stimuli.
Dysregulation of p70 S6 kinase 2 activity has been implicated in the development and progression of cancer and other diseases. Therefore, studying the function and regulation of p70 S6 kinase 2 is essential for gaining insight into the molecular mechanisms underlying these conditions and identifying potential therapeutic targets. The p70 S6 Kinase 2 Polyclonal Antibody (CAB9100) provides researchers with a reliable tool for investigating the role of this crucial protein in health and disease.
Product Name:
p70 S6 Kinase 2 Rabbit Monoclonal Antibody
SKU:
CAB9100
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human p70 S6 Kinase 2 (Q9UBS0).
Sequence:
MAAV FDLD LETE EGSE GEGE PELS PADA CPLA ELRA AGLE PVGH YEEV ELTE TSVN VGPE RIGP HCFE LLRV LGKG GYGK VFQV RKVQ GTNL GKIY AMKV LRKA KIVR NAKD TAHT RAER
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Purification Method:
Affinity purification
Gene ID:
6199
Clone Number:
ARC1790
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using p70 S6 Kinase 2 Rabbit mAb (CAB9100) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
