The Anti-OSD-LT Antibody (CAB20318) is a highly specific antibody designed for research involving OSD-LT, a cell surface molecule implicated in immune regulation. Raised in rabbits, this polyclonal antibody is highly reactive with human samples and is validated for use in various applications such as Western blotting. By binding to the OSD-LT protein, this antibody enables detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.
OSD-LT, also known as immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammation and inhibiting allergic reactions. Its significance in immune response modulation makes it a valuable target for research into diseases like cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the activity of OSD-LT is essential for developing therapies that harness or modulate immune function in these contexts.
Product Name:
OsDLT Rabbit Polyclonal Antibody
SKU:
CAB20318
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Oryza sativa
Immunogen:
Recombinant protein of Oryza sativa OsDLT.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
DLT; OsGRAS-32; D62; GS6; SMOS2; OsDLT
Positive Sample:
young leaves (10 d),stems (before flower),leaves sheath (before flower)
Conjugate:
Unconjugated
Cellular Localization:
nucleus
Calculated MW:
66kDa
Observed MW:
66kDa
Probable transcription factor that acts as positivie regulator of brassinosteroid (BR) signaling. Functions downstream of BRI1 and GSK2 to modulate BR responses. Acts as a direct target of GSK2 kinase to mediate BR responses. Involved in feedback inhibition of BR biosynthetic genes. Repressed by BZR1. Cooperatively functions in a transactivating complex with SMOS1 to enhance the transcription of the SMOS1 target PHI-1, and regulate plant organ size. Interaction between SMOS1 and DLT is a crosstalk point for auxin and brassinosteroid signaling
Purification Method:
Affinity purification
Gene ID:
4339978
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various tissues from the japonica rice (Oryza sativa L.) variety Zhonghua 11, using OsDLT Rabbit pAb (CAB20318) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
